Safest setup with Cheyenne Hawk Thunder type of tattoo machines.

Biggest issue with this king of machine is original grip provided by manufacturer that is impossible to take apart for proper cleaning and as a common (bad) standard in industry is not to autoclave them and even worst not even cover them with any barrier film. Best alternative so far is to go with disposable grips and fair amount of barrier films and tapes and thin it can be set up and broken down with some sort of peace of mind.

Follow best contamination avoidance practices and stay safe